AACR Project GENIE: Powering Precision Medicine through an International Consortium
AACR Project GENIE pools tumor sequencing results and clinical data from major cancer centers into one shared registry. The first data release described here covered nearly 19,000 patients. The registry lets researchers ask questions no single institution could answer alone: how often a mutation appears in a rare cancer, or how patients with a given variant fared on a given therapy.
I contributed as part of the consortium through GenomOncology’s work on the informatics side. GENIE showed that real-world genomic evidence works at scale when institutions agree on shared structure — the same premise behind the curated knowledge bases and biomedical data tools I build today.